Synopsis
In the OKINADA study, we will test a biological drug approved for the treatment of such conditions as rheumatoid arthritis and ankylosing spondylitis, to see if it will help with the pain and stiffness experienced by patients with osteoarthritis of the knee.More information about biologics and the OKINADA study can be found at www.OKINADA.com.
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Tools
OKINADA BMI Calculator
Upper Tertile BMI by age and gender:
All subjects must have a BMI less than or equal to 34.0 (for protocol version 1.7) or 40.0 (for protocol version 1.9).
Kellgren-Lawrence Grading Scale for Knee OA
Grade 1: Doubtful joint space narrowing (JSN) and possible osteophytic lipping | Grade 2: Definite osteophytes and possible JSN on anteroposterior weight-bearing radiograph | Grade 3: Multiple osteophytes, definite JSN, sclerosis, possible bony deformity | Grade 4: Large osteophytes, marked JSN, severe sclerosis and definite bony deformity |